Some With Autism Diagnosis Can Recover, Study Finds

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Doctors have long believed that disabling autistic disorders last a lifetime, but a new study has found that some children who exhibit signature symptoms of the disorder recover completely.


The study, posted online on Wednesday by the Journal of Child Psychology and Psychiatry, is the largest to date of such extraordinary cases and is likely to alter the way that scientists and parents think and talk about autism, experts said.


Researchers on Wednesday cautioned against false hope. The findings suggest that the so-called autism spectrum contains a small but significant group who make big improvements in behavioral therapy for unknown, perhaps biological reasons, but that most children show much smaller gains. Doctors have no way to predict which children will do well.


Researchers have long known that between 1 and 20 percent of children given an autism diagnosis no longer qualify for one a few years or more later. They have suspected that in most cases the diagnosis was mistaken; the rate of autism diagnosis has ballooned over the past two decades, and some research suggests that it has been loosely applied.


The new study should put some of that skepticism to rest.


“This is the first solid science to address this question of possible recovery, and I think it has big implications,” said Sally Ozonoff of the MIND Institute at the University of California, Davis, who was not involved in the research. “I know many of us as would rather have had our tooth pulled than use the word ‘recover,’ it was so unscientific. Now we can use it, though I think we need to stress that it’s rare.”


She and other experts said the findings strongly supported the value of early diagnosis and treatment.


In the study, a team led by Deborah Fein of the University of Connecticut at Storrs recruited 34 people who had been diagnosed before the age of 5 and no longer had any symptoms. They ranged in age from 8 to 21 years old and early in their development were in the higher-than-average range of the autism spectrum. The team conducted extensive testing of its own, including interviews with parents in some cases, to gauge current social and communication skills.


The debate over whether recovery is possible has simmered for decades and peaked in 1987, when the pioneering autism researcher O. Ivar Lovaas reported that 47 percent of children with the diagnosis showed full recovery after undergoing a therapy he had devised. This therapy, a behavioral approach in which increments of learned skills garner small rewards, is the basis for the most effective approach used today; still, many were skeptical and questioned his definition of recovery.


Dr. Fein and her team used standardized, widely used measures and found no differences between the group of 34 formerly diagnosed people and a group of 34 matched control subjects who had never had a diagnosis.


“They no longer qualified for the diagnosis,” said Dr. Fein, whose co-authors include researchers from Queens University in Kingston, Ontario; Children’s Hospital of Philadelphia; the Institute of Living in Hartford; and the Child Mind Institute in New York. “I want to stress to parents that it’s a minority of kids who are able to do this, and no one should think they somehow missed the boat if they don’t get this outcome.”


On measures of social and communication skills, the recovered group scored significantly better than 44 peers who had a diagnosis of high-functioning autism or Asperger’s syndrome.


Dr. Fein emphasized the importance of behavioral therapy. “These people did not just grow out of their autism,” she said. “I have been treating children for 40 years and never seen improvements like this unless therapists and parents put in years of work.”


The team plans further research to learn more about those who are able to recover. No one knows which ingredients or therapies are most effective, if any, or if there are patterns of behavior or biological markers that predict such success.


“Some children who do well become quite independent as adults but have significant anxiety and depression and are sometimes suicidal,” said Dr. Fred Volkmar, the director of the Child Study Center at the Yale University School of Medicine. There are no studies of this group, he said.


That, because of the new study, is about to change.


Read More..

Some With Autism Diagnosis Can Recover, Study Finds

Label:


Doctors have long believed that disabling autistic disorders last a lifetime, but a new study has found that some children who exhibit signature symptoms of the disorder recover completely.


The study, posted online on Wednesday by the Journal of Child Psychology and Psychiatry, is the largest to date of such extraordinary cases and is likely to alter the way that scientists and parents think and talk about autism, experts said.


Researchers on Wednesday cautioned against false hope. The findings suggest that the so-called autism spectrum contains a small but significant group who make big improvements in behavioral therapy for unknown, perhaps biological reasons, but that most children show much smaller gains. Doctors have no way to predict which children will do well.


Researchers have long known that between 1 and 20 percent of children given an autism diagnosis no longer qualify for one a few years or more later. They have suspected that in most cases the diagnosis was mistaken; the rate of autism diagnosis has ballooned over the past two decades, and some research suggests that it has been loosely applied.


The new study should put some of that skepticism to rest.


“This is the first solid science to address this question of possible recovery, and I think it has big implications,” said Sally Ozonoff of the MIND Institute at the University of California, Davis, who was not involved in the research. “I know many of us as would rather have had our tooth pulled than use the word ‘recover,’ it was so unscientific. Now we can use it, though I think we need to stress that it’s rare.”


She and other experts said the findings strongly supported the value of early diagnosis and treatment.


In the study, a team led by Deborah Fein of the University of Connecticut at Storrs recruited 34 people who had been diagnosed before the age of 5 and no longer had any symptoms. They ranged in age from 8 to 21 years old and early in their development were in the higher-than-average range of the autism spectrum. The team conducted extensive testing of its own, including interviews with parents in some cases, to gauge current social and communication skills.


The debate over whether recovery is possible has simmered for decades and peaked in 1987, when the pioneering autism researcher O. Ivar Lovaas reported that 47 percent of children with the diagnosis showed full recovery after undergoing a therapy he had devised. This therapy, a behavioral approach in which increments of learned skills garner small rewards, is the basis for the most effective approach used today; still, many were skeptical and questioned his definition of recovery.


Dr. Fein and her team used standardized, widely used measures and found no differences between the group of 34 formerly diagnosed people and a group of 34 matched control subjects who had never had a diagnosis.


“They no longer qualified for the diagnosis,” said Dr. Fein, whose co-authors include researchers from Queens University in Kingston, Ontario; Children’s Hospital of Philadelphia; the Institute of Living in Hartford; and the Child Mind Institute in New York. “I want to stress to parents that it’s a minority of kids who are able to do this, and no one should think they somehow missed the boat if they don’t get this outcome.”


On measures of social and communication skills, the recovered group scored significantly better than 44 peers who had a diagnosis of high-functioning autism or Asperger’s syndrome.


Dr. Fein emphasized the importance of behavioral therapy. “These people did not just grow out of their autism,” she said. “I have been treating children for 40 years and never seen improvements like this unless therapists and parents put in years of work.”


The team plans further research to learn more about those who are able to recover. No one knows which ingredients or therapies are most effective, if any, or if there are patterns of behavior or biological markers that predict such success.


“Some children who do well become quite independent as adults but have significant anxiety and depression and are sometimes suicidal,” said Dr. Fred Volkmar, the director of the Child Study Center at the Yale University School of Medicine. There are no studies of this group, he said.


That, because of the new study, is about to change.


Read More..

The Lede Blog: Video Shows Flaming Wreckage After Helicopter Crash in London

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Footage of the flaming wreckage of a helicopter crash in London on Wednesday posted on YouTube by Nic Walker.

Video and photographs posted online by witnesses showed smoke and fire on a street in central London after a helicopter crash on Wednesday. The police said the aircraft hit a crane atop a residential tower, exploding into flames and hurtling to the ground during the morning rush, my colleagues Lark Turner and Alan Cowell reported.

The pilot, identified by his employer as Capt. Pete Barnes, 50, was the only occupant in the aircraft. He and one person on the ground were killed, and at least nine were injured after the helicopter hit the crane on one of Europe’s tallest residential towers, known as The Tower.

One witness described seeing cars on fire and people screaming and running for their lives, in a brief video interview. A worker in the area told Britain’s Channel 4 News that the helicopter was “struggling” and making “funny noises” before it crashed.

A video report from Britain’s Channel 4 News.

A journalist named Mike Smith posted a photograph of the crane on Twitter, and footage from Britain’s Sky News showed the location near the Thames.

Footage of the crash site, from Britain’s Sky News.

The most telling video and photographs, perhaps, were recorded by Nic Walker, a resident of Vauxhall, the area where the crash took place.

Later in the day, after the images he posted on YouTube and Twitter were widely published and broadcast, Mr. Walker wrote on his @nic0 Twitter feed that he had no interest in making money from the episode.

The Facebook page of RotorMotion, the company for which Captain Barnes was flying, carried condolence messages. In a statement, RotorMotion said he was a very skilled pilot who had left behind a wife and children.

A spokesman for the company said that on Wednesday, Captain Barnes was on an executive charter flight and was on his way to pick up a client at Elstree Aerodrome. “We understand that he was diverting to Battersea heliport as a result of poor weather over Elstree and was approaching Battersea when the incident occurred,” said Paul Blezard.

Captain Barnes had an extensive career in medical ambulance flights. A British race car driver, Jolyon Palmer, wrote on Twitter that the pilot had helped to save his life in 2007.

The Yorkshire Post reported that Captain Barnes had flown with the air ambulance services there. In a 2006 profile of the pilot that discussed his work on films including the James Bond thriller “Die Another Day,” The Post quoted Captain Barnes saying, “It’s not as glamorous as everyone thinks — there’s a lot of hanging about and then suddenly you’re activated and you have to get on and do your stuff.”

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Pushing France Onto the Digital Stage

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PARIS — When the most prominent new face in France’s effort to oversee the new economy speaks, her pronouncements may be followed almost as closely in Silicon Valley and Seoul as in Paris.


Fleur Pellerin, a deputy finance minister, is the point woman in President François Hollande’s campaign to stimulate innovation. But in trying to put a French imprint on the digital economy, she has been drawn into a growing number of disputes with U.S. technology companies like Google, Twitter and Amazon.


In South Korea, it is Ms. Pellerin’s personal story that fascinates. Abandoned on the streets of Seoul as a newborn, she was taken in by a French family who raised her in the suburbs of Paris. While more than 150,000 South Korean children have been adopted by foreign parents since the Korean War, only one, Ms. Pellerin, has risen to the top ranks of the French government.


In one of the clearest signals yet from the French Finance Ministry that the government is intent on making the Internet conform to French law and custom, Ms. Pellerin last week waded into a dispute involving Google, whose advertising had been blocked by a French Internet service provider, Free.


The move was widely seen as an attempt by Free to force Google to pay for network access. As a preliminary step, Ms. Pellerin ordered Free to restore full service, but she made it clear that she thought the French company had a legitimate grievance.


The appointment of Ms. Pellerin last May, after Mr. Hollande’s election, prompted talk of a new orientation in French technology policy, where mistrust of foreign companies has sometimes been the guiding principle.


Ms. Pellerin, 39, is the first French government minister of Asian extraction. Although she has never visited the land of her birth, in French technology circles her rise fostered a perhaps naïve hope: Might Ms. Pellerin transform France into a European version of South Korea, where ultrahigh-speed broadband is ubiquitous and electronics giants like Samsung and LG have become world-beaters?


“I would like to make France one of the top nations in terms of digital innovation,” Ms. Pellerin said during a recent interview in her office at the Finance Ministry, which juts out over the Seine in eastern Paris like a giant, modern version of a medieval river toll barrier. “If we don’t act in the next few years it will be too late.”


Yet anyone expecting a drastic break with French governing traditions might be disappointed by Ms. Pellerin. After her unusual arrival in France, her upbringing and rise through the system were largely indistinguishable from that of many native-born members of the French administration.


Raised by middle-class parents — her father, who has a doctorate in nuclear physics, is a small-business owner — Ms. Pellerin grew up in two Paris suburbs, gritty Montreuil and wealthier Versailles. A promising student from the start, she was educated at elite institutions, including Sciences Po and the École Nationale d’Administration, which serve as finishing schools for the country’s ruling class. Before joining Mr. Hollande’s government, she was a magistrate at the Cour des Comptes, a body that audits the public finances, and worked in public relations.


Ms. Pellerin’s husband, Laurent Olléon, is also in government service, as an official in the office of Marylise Lebranchu, the minister for the reform of the state and decentralization. Ms. Pellerin has an 8-year-old daughter from a previous marriage.


In her new role in government, Ms. Pellerin has become the central figure in Mr. Hollande’s drive to establish “digital sovereignty” — the principle that French rules should apply to international Internet companies, which sometimes hover elusively beyond the reach of the national authorities. This has prompted clashes with a growing number of American technology companies.


Overseeing investigations of these companies on taxation and other matters, even while wooing them to invest in France, is a balancing act, Ms. Pellerin acknowledged.


“It’s not a crusade against Americans,” she said. “We are just trying to put everyone on a level playing field.”


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Rights Group Reports on Abuses of Surveillance and Censorship Technology

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A Canadian human rights monitoring group has documented the use of American-made Internet surveillance and censorship technology by more than a dozen governments, some with harsh human rights policies like Syria, China and Saudi Arabia.







Jakub Dalek of the Munk School of Global Affairs.







Thor Swift for The New York Times

Morgan Marquis-Boire led the research with Mr. Dalek.






The Citizen Lab Internet research group, based at the Munk School of Global Affairs at the University of Toronto, used computer servers to scan for the distinctive signature of gear made by Blue Coat Systems of Sunnyvale, Calif.


It determined that Egypt, Kuwait, Qatar, Saudi Arabia and the United Arab Republic employed a Blue Coat system that could be used for digital censorship. The group also determined that Bahrain, China, India, Indonesia, Iraq, Kenya, Kuwait, Lebanon, Malaysia, Nigeria, Qatar, Russia, Saudi Arabia, South Korea, Singapore, Thailand, Turkey and Venezuela used equipment that could be used for surveillance and tracking.


The authors said they wanted to alert the public that there was a growing amount of surveillance and content-filtering technology distributed throughout the Internet. The technology is not restricted from export by the State Department, except to countries that are on embargo lists, like Syria, Iran and North Korea.


“Our findings support the need for national and international scrutiny of the country Blue Coat implementations we have identified, and a closer look at the global proliferation of dual-use information and communications technology,” the group noted. “We hope Blue Coat will take this as an opportunity to explain their due diligence process to ensure that their devices are not used in ways that violate human rights.”


A spokesman for Blue Coat Systems said the firm had not seen the final report and was not prepared to comment.


In 2011, several groups, including Telecomix and Citizen Labs, raised concerns that Blue Coat products were being used to find and track opponents of the Syrian government. The company initially denied that its equipment had been sold to Syria, which is subject to United States trade sanctions.


Shortly afterward, Blue Coat reversed itself and acknowledged that the systems were indeed in Syria, but it said that the devices had been shipped to a distributor in Dubai, and said that it thought that they had been destined for the Iraqi Ministry of Communications.


The Citizen Lab research project was led by Morgan Marquis-Boire and Jakub Dalek. Mr. Marquis-Boire, a Google software engineer, has during the last year been involved in a variety of research projects aimed at exposing surveillance tools used by authoritarian regimes. He said that he carefully segregated his work at Google from his human rights research.


Last year, Mr. Marquis-Boire used computer servers to identify the use of an intelligence-oriented surveillance software program, called FinSpy, which was being used by Bahrain to track opposition activists.


On a hunch last month, the researchers used the Shodan search engine, a specialized Internet tool intended to help identify computers and software services that were connected to the Internet. They were able to identify a number of the Blue Coat systems that are used for content filtering and for “deep packet inspection,” a widely used technology for detecting and controlling digital content as it travels through the Internet.


The researchers stressed that they were aware that there were both benign and harmful uses for the Blue Coat products identified as ProxySG, which functions as a Web filter, and a second system, PacketShaper, which can detect about 600 Web applications and can be used to control undesirable Web traffic.


“I’m not trying to completely demonize this technology,” Mr. Marquis-Boire said.


The researchers also noted that the equipment does not directly fall under the dual-use distinction employed by the United States government to control the sale of equipment that has both military and civilian applications, but it can be used for both political and intelligence applications by authoritarian governments.


“Syria is subject to U.S. export sanctions,” said Sarah McKune, a senior researcher at the Citizen Lab. “When it comes to other countries that aren’t subject to U.S. sanctions it’s a more difficult situation. There could still be significant human rights impact.”


The researchers also noted that a large number of American and foreign companies supplied similar gear in what Gartner, the market research firm, described as a $1.02 billion market in a report issued in May 2012.


The researchers said that some American security technology companies, like Websense, had taken strong human rights stands, but had declined to grapple with the issue of the possible misuse of the technology.


This article has been revised to reflect the following correction:

Correction: January 16, 2013

An earlier version of this article misspelled the surname of a senior researcher at the Citizen Lab Internet research group. She is Sarah McKune, not McCune.



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Well: Boosting Your Flu Shot Response

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Phys Ed

Gretchen Reynolds on the science of fitness.

As this year’s influenza season continues to take its toll, those procrastinators now hurrying to get a flu shot might wish to know that exercise may amplify the flu vaccine’s effect. And for maximal potency, the exercise should be undertaken at the right time and involve the right dosage of sweat, according to several recent reports.

Flu shots are one of the best ways to lessen the risk of catching the disease. But they are not foolproof. By most estimates, the yearly flu vaccine blocks infection 50 to 70 percent of the time, meaning that some of those being inoculated gain little protection. The more antibodies someone develops, the better their protection against the flu, generally speaking. But for some reason, some people’s immune systems produce fewer antibodies to the influenza virus than others’ do.

Being physically fit has been found in many studies to improve immunity in general and vaccine response in particular. In one notable 2009 experiment, sedentary, elderly adults, a group whose immune systems typically respond weakly to the flu vaccine, began programs of either brisk walking or a balance and stretching routine. After 10 months, the walkers had significantly improved their aerobic fitness and, after receiving flu shots, displayed higher average influenza antibody counts 20 weeks after a flu vaccine than the group who had stretched.

But that experiment involved almost a year of dedicated exercise training, a prospect that is daunting to some people and, in practical terms, not helpful for those who have entered this flu season unfit.

So scientists have begun to wonder whether a single, well-calibrated bout of exercise might similarly strengthen the vaccine’s potency.

To find out, researchers at Iowa State University in Ames recently had young, healthy volunteers, most of them college students, head out for a moderately paced 90-minute jog or bike ride 15 minutes after receiving their flu shot. Other volunteers sat quietly for 90 minutes after their shot. Then the researchers checked for blood levels of influenza antibodies a month later.

Those volunteers who had exercised after being inoculated, it turned out, exhibited “nearly double the antibody response” of the sedentary group, said Marian Kohut, a professor of kinesiology at Iowa State who oversaw the study, which is being prepared for publication. They also had higher blood levels of certain immune system cells that help the body fight off infection.

To test how much exercise really is required, Dr. Kohut and Justus Hallam, a graduate student in her lab, subsequently repeated the study with lab mice. Some of the mice exercised for 90 minutes on a running wheel, while others ran for either half as much time (45 minutes) or twice as much (3 hours) after receiving a flu shot.

Four weeks later, those animals that, like the students, had exercised moderately for 90 minutes displayed the most robust antibody response. The animals that had run for three hours had fewer antibodies; presumably, exercising for too long can dampen the immune response. Interestingly, those that had run for 45 minutes also had a less robust response. “The 90-minute time point appears to be optimal,” Dr. Kohut says.

Unless, that is, you work out before you are inoculated, another set of studies intimates, and use a dumbbell. In those studies, undertaken at the University of Birmingham in England, healthy, adult volunteers lifted weights for 20 minutes several hours before they were scheduled to receive a flu shot, focusing on the arm that would be injected. Specifically, they completed multiple sets of biceps curls and side arm raises, employing a weight that was 85 percent of the maximum they could lift once. Another group did not exercise before their shot.

After four weeks, the researchers checked for influenza antibodies. They found that those who had exercised before the shot generally displayed higher antibody levels, although the effect was muted among the men, who, as a group, had responded to that year’s flu vaccine more robustly than the women had.

Over all, “we think that exercise can help vaccine response by activating parts of the immune system,” said Kate Edwards, now a lecturer at the University of Sydney, and co-author of the weight-training study.

With the biceps curls, she continued, the exercises probably induced inflammation in the arm muscles, which may have primed the immune response there.

As for 90 minutes of jogging or cycling after the shot, it probably sped blood circulation and pumped the vaccine away from the injection site and to other parts of the body, Dr. Kohut said. The exercise probably also goosed the body’s overall immune system, she said, which, in turn, helped exaggerate the vaccine’s effect.

But, she cautions, data about exercise and flu vaccines is incomplete. It is not clear, for instance, whether there is any advantage to exercising before the shot instead of afterward, or vice versa; or whether doing both might provoke the greatest response – or, alternatively, be too much and weaken response.

So for now, she says, the best course of action is to get a flu shot, since any degree of protection is better than none, and, if you can, also schedule a visit to the gym that same day. If nothing else, spending 90 minutes on a stationary bike will make any small twinges in your arm from the shot itself seem pretty insignificant.

Read More..

Well: Boosting Your Flu Shot Response

Label:
Phys Ed

Gretchen Reynolds on the science of fitness.

As this year’s influenza season continues to take its toll, those procrastinators now hurrying to get a flu shot might wish to know that exercise may amplify the flu vaccine’s effect. And for maximal potency, the exercise should be undertaken at the right time and involve the right dosage of sweat, according to several recent reports.

Flu shots are one of the best ways to lessen the risk of catching the disease. But they are not foolproof. By most estimates, the yearly flu vaccine blocks infection 50 to 70 percent of the time, meaning that some of those being inoculated gain little protection. The more antibodies someone develops, the better their protection against the flu, generally speaking. But for some reason, some people’s immune systems produce fewer antibodies to the influenza virus than others’ do.

Being physically fit has been found in many studies to improve immunity in general and vaccine response in particular. In one notable 2009 experiment, sedentary, elderly adults, a group whose immune systems typically respond weakly to the flu vaccine, began programs of either brisk walking or a balance and stretching routine. After 10 months, the walkers had significantly improved their aerobic fitness and, after receiving flu shots, displayed higher average influenza antibody counts 20 weeks after a flu vaccine than the group who had stretched.

But that experiment involved almost a year of dedicated exercise training, a prospect that is daunting to some people and, in practical terms, not helpful for those who have entered this flu season unfit.

So scientists have begun to wonder whether a single, well-calibrated bout of exercise might similarly strengthen the vaccine’s potency.

To find out, researchers at Iowa State University in Ames recently had young, healthy volunteers, most of them college students, head out for a moderately paced 90-minute jog or bike ride 15 minutes after receiving their flu shot. Other volunteers sat quietly for 90 minutes after their shot. Then the researchers checked for blood levels of influenza antibodies a month later.

Those volunteers who had exercised after being inoculated, it turned out, exhibited “nearly double the antibody response” of the sedentary group, said Marian Kohut, a professor of kinesiology at Iowa State who oversaw the study, which is being prepared for publication. They also had higher blood levels of certain immune system cells that help the body fight off infection.

To test how much exercise really is required, Dr. Kohut and Justus Hallam, a graduate student in her lab, subsequently repeated the study with lab mice. Some of the mice exercised for 90 minutes on a running wheel, while others ran for either half as much time (45 minutes) or twice as much (3 hours) after receiving a flu shot.

Four weeks later, those animals that, like the students, had exercised moderately for 90 minutes displayed the most robust antibody response. The animals that had run for three hours had fewer antibodies; presumably, exercising for too long can dampen the immune response. Interestingly, those that had run for 45 minutes also had a less robust response. “The 90-minute time point appears to be optimal,” Dr. Kohut says.

Unless, that is, you work out before you are inoculated, another set of studies intimates, and use a dumbbell. In those studies, undertaken at the University of Birmingham in England, healthy, adult volunteers lifted weights for 20 minutes several hours before they were scheduled to receive a flu shot, focusing on the arm that would be injected. Specifically, they completed multiple sets of biceps curls and side arm raises, employing a weight that was 85 percent of the maximum they could lift once. Another group did not exercise before their shot.

After four weeks, the researchers checked for influenza antibodies. They found that those who had exercised before the shot generally displayed higher antibody levels, although the effect was muted among the men, who, as a group, had responded to that year’s flu vaccine more robustly than the women had.

Over all, “we think that exercise can help vaccine response by activating parts of the immune system,” said Kate Edwards, now a lecturer at the University of Sydney, and co-author of the weight-training study.

With the biceps curls, she continued, the exercises probably induced inflammation in the arm muscles, which may have primed the immune response there.

As for 90 minutes of jogging or cycling after the shot, it probably sped blood circulation and pumped the vaccine away from the injection site and to other parts of the body, Dr. Kohut said. The exercise probably also goosed the body’s overall immune system, she said, which, in turn, helped exaggerate the vaccine’s effect.

But, she cautions, data about exercise and flu vaccines is incomplete. It is not clear, for instance, whether there is any advantage to exercising before the shot instead of afterward, or vice versa; or whether doing both might provoke the greatest response – or, alternatively, be too much and weaken response.

So for now, she says, the best course of action is to get a flu shot, since any degree of protection is better than none, and, if you can, also schedule a visit to the gym that same day. If nothing else, spending 90 minutes on a stationary bike will make any small twinges in your arm from the shot itself seem pretty insignificant.

Read More..

India Ink: In New Delhi, Women Marry Up and Men Are Left Behind

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There’s an unexpected problem in New Delhi’s high-end marriage market, according to Gopal Suri, who has been a marriage broker for two decades.

There are too few “quality” men, he said in a recent interview, as a growing pool of young women with unprecedented levels of education are seeking and making matches with educated men from higher socioeconomic groups.

The repercussions from India’s skewed sex ratios are being felt at all economic levels, including Delhi’s wealthiest families. For every 1,000 men in urban India, there are only 926 women, according to India’s census. In Delhi’s urban area, that figure for women drops even lower, to 867. Poor migrant laborers, who travel to the city for work, account for some of the gender disparity, but there is still a large pool of single middle-class men in Delhi.

The well-educated women’s upward mobility has a cascading effect, he said. The less-educated men from wealthy, but not incredibly rich, families get left behind. (Mr. Suri’s business in south Delhi, A to Z Matchmaking, caters to households with an annual income of 5 million rupees ($90,000) to more than 50 million rupees ($900,000).

There are plenty of young men in Delhi with money, he said, but their education levels fall short compared with other women in their class bracket. Educated women in general can afford to be choosy because they are the minority in the marriage market.

“Literacy-wise, there aren’t many boys,” said Mr. Suri.

These empowered women are increasingly discerning when it comes to marriage. In this age of tell-all social networks and social media, it’s not too difficult to research prospective mates, Mr. Suri said. “Some men are into gay activities, some are into drugs or drink too much,” he said. “Then the market finds out and so his reputation goes down. This is the age of Facebook.”

For men who are in the lowest tiers of society, “there is frustration,” he said, as they have limited prospects for marriage or jobs. “He’s not going to get anything or anyone,” he said.

The male frustration, as Mr. Suri dubbed it, arises because the men can’t accept that women in their socioeconomic class are moving swiftly ahead of them. Sometimes these men lash out, and women bear the brunt of it, Mr. Suri said, alluding to the recent attention to violence against women in India’s capital.

These men wind up “on the roads and frustrated, and try to do something, somehow,” he said. “When he drinks, it is like icing on the cake.”

Mr. Suri brokers about 200 marriages a year. In 2008 and 2009, Mr. Suri said, he saw a huge spike in weddings when young, educated men who had left India for opportunities abroad returned to the motherland, further diminishing the prospects for the men in Delhi.

Demographics aside, the primary factors for determining compatibility in India’s marriage market are economics and education, he said.

Other factors do come into play, he said: “Are they cultured? Intellectually compatible? Personally compatible?” But, he said, “ultimately, people pay most attention to finances, in this day and age especially. Money is the floating god.”

Still, highly educated women don’t necessarily get the perfect mates, Mr. Suri said, and most women have to compromise “on one thing or the other.”

“If she does get married, it’s usually out of compulsion,” he said. “This is why divorce has gone up.”

And when women are more educated then their partners, “it just doesn’t match,” Mr. Suri said. “The boy gets an inferiority complex, and the girl starts thinking, ‘Where can I take him?’ ”

The “marrying up” trend isn’t seen among very wealthy women, he said, since the pool of very rich eligible men has shrunk.

“The girls have become 35 or 40 and can’t get married,” Mr. Suri said. “First they were choosy,” he said, and now they are too old.

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TIMESCAST: Suicide Prompts Investigation at M.I.T.

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January 14, 2013By Fritzie Andrade, Zena Barakat, Axel Gerdau, David Frank and Pedro Rafael Rosado

TimesCast Media+Tech: M.I.T. examines its involvement in the suicide of Aaron Swartz. The post-Golden Globe marketing push by movie studios. Networks revisit conversations about violence.

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California to Give Web Courses a Big Trial

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A plan to offer an array of online college classes at a California state university could, if the students are successful, open the door to teaching hundreds of thousands of California students at a lower cost via the Internet.


Udacity, a Silicon Valley start-up that creates online college classes, will announce a deal on Tuesday with San Jose State University for a series of remedial and introductory courses.


Because the courses are intended to involve the classroom instructor, it could also help to blunt professors’ unease with the online classes. 


The state university’s deal with Udacity is also the first time that professors at a university have collaborated with a provider of a MOOC — massive open online course — to create for-credit courses with students watching videos and taking interactive quizzes, and receiving support from online mentors.


Eventually, such courses could be offered to hundreds of thousands of students in the state.


California Gov. Jerry Brown, who has been pushing state universities to move more aggressively into online education, approached the company to come up with a technological solution for what has become a vexing challenge for the state.


Ellen N. Junn, provost and vice president for academic affairs at the university in San Jose, said the California State University System faces a crisis because more than 50 percent of entering students cannot meet basic requirements.


“They graduate from high school, but they cannot pass our elementary math and English placement tests,” she said.


The Udacity pilot program will include a remedial algebra course, a college-level algebra course and introductory statistics.


For the pilot project starting this month, however, the courses will be limited to 300 students — half from San Jose State University, and half from local community colleges and high schools — who will pay lower than usual tuition. The cost of each three-unit course will be $150, significantly less than regular San Jose State tuition. Sebastian Thrun, one of the founders of Udacity, would not disclose how much the company would be paid for its participation.


San Jose State will receive funds from the National Science Foundation to study the effectiveness of the new online classroom design.


Open online courses exploded in American higher education in 2011 after Mr. Thrun, a nationally known artificial-intelligence researcher at Stanford, and Peter Norvig, Google’s director of research, offered to teach an introductory artificial-intelligence course online. More than 160,000 students initially registered for the class.


After two other Stanford courses each attracted more than 100,000 students, Dr. Thrun started his venture. Two other Stanford computer scientists, Andrew Ng and Daphne Koller, also established a competing private company, Coursera, to develop technologies necessary to change the reach and effectiveness of online education.


The courses have rapidly moved from the periphery to the center of higher education policy as a growing number of schools have begun experimenting with ways to offer the courses for credit toward a degree.


EdX, a university collaboration initiated by the Massachusetts Institute of Technology and Harvard last year, this month will begin offering some of its courses at two Massachusetts community colleges, in a blended format.


Recently edX completed a pilot offering of its difficult circuits and electronics course at San Jose State to stunning results: while 40 percent of the students in the traditional version of the class got a grade of C or lower, only 9 percent in the blended edX class got such a low grade.


Last fall, for the first time, Udacity’s courses were tried on a small group of struggling high school students, at the Winfree Academy Charter School system, a cluster of schools near Dallas-Fort Worth created to help struggling students and reclaim dropouts.


“I was a little scared to put our kids, who are struggling and at risk of dropping out, into a class written by a Stanford professor,” said Melody Chalkley, Winfree’s founder. “But of the 23 students who used Udacity, one withdrew from the school, and the other 22 all finished successfully. And two young women got through the whole physics course in just two weeks.”


This article has been revised to reflect the following correction:

Correction: January 15, 2013

An earlier version of this article misstated the name of a California university faculty group. It is the California Faculty Association, not the California Teachers Association. The article also misstated the nature of the courses that San Jose State University will offer with Udacity. The courses will involve students watching videos and taking interactive quizzes; they will not be blended courses with students first watching videos on their own, and then coming to class to work on assignments with a professor.



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